To some extent, I’d say that if you’re motivated enough, just pick up whatever you’re interested in and try it. The worst that can happen is that you’ll spend an hour slogging through a couple of sentences, decide that it’s too much work and put it away, and come back in ten levels to see how much you’ve progressed.
For reading in general, being comfortable with Japanese sentence structure is going to be a bigger hurdle than vocabulary. As long as you’re able to untangle Japanese sentences okay, it’s really just a function of how much time you’re willing to spend with a dictionary from there.
I’d also guess that adult-oriented titles are almost never going to bother putting furigana on things, so if they use a lot of kanji, you won’t be able to look up words by reading as easily. It will help if you know how to use some tool to look up kanji by radical or handwriting recognition.
As has been said, reading for the first time is a slog no matter how much you study, just like dancing is hard the first time no matter how many dance videos you watch. So don’t feel like there’s any perfect level where it will suddenly become easy.
(For what it’s worth, I personally felt like written material transitioned from “giant wall of incomprehensible kanji” to “giant wall of kanji I vaguely recognize” at around 20 or so. I think there was a thread recently that did some math supporting the idea that 20 is roughly a turning point when most of the really important kanji are out of the way.)