No. Disease actually wiped out the majority, just as the same diseases were wiping out people across Europe and Africa… a very unfortunate and unintentional side effect of world travel in a time when epidemiology was not well understood. Also, the native populations were very diverse, with many tribes already battling each other before the colonists started arriving.
When the colonists arrived, there were both good and bad relations between natives and colonists, often depending on the particular tribes’ view of outsiders. In some cases, they formed mutually beneficial trade and peaceful coexistence. In other cases, tribes immediately went to war with colonists simply because they were there (and that was their right to defend their land).
Many of the early U.S. government leaders admired the peaceful societies of some of the tribes. George Washington led many efforts to iron out conflicts and preserve the culture and land of native tribes. But the government at that time was not equipped to control the flood of colonists, many of whom continued to encroach on lands preserved by treaty, and that started a lot of conflict, much of which was very brutal. On both sides. In some cases, entire colonies were wiped out. In other cases, entire tribes were wiped out. Conflict is never pretty, and rarely does one side bear all of the fault.
Anyway, Wikipedia has a surprisingly good article:
While it doesn’t go into much depth about the relations between colonists and natives (well, it does talk a lot about the spaniards, but not as much about the later european colonists, which is the most interesting part to me), it seems to do a good job of sampling the diverse views about population decline.
It’s also interesting to note that native american population is actually about 2% of the population if you count mixed race, and 0.9% if you count only non-mixed. It’s a small percentage, but is still 6.6million (mixed) or 2.9million (non-mixed).
[sorry for derailing the thread, by the way. I hope I’ve at least kept it interesting and peaceful, though]